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Kochi Pascual-Marqui

Fakultäten » Medizinische Fakultät » Psychiatrische Universitätsklinik » Psychiatrie, Psychotherapie und Psychosomatik, Klinik für » Prof. Dr. Daniel Hell (emeritiert) » Kochi Pascual-Marqui

Completed research project

Title / Titel Multimodal Functional Imaging of the Human Brain with Low Resolution Brain Electromagnetic Tomography (LORETA) and fMRI.
PDF Abstract (PDF, 14 KB)
Summary / Zusammenfassung This project is concerned with the analysis of functional images of the human brain obtained from two different modalities: electric activity (LORETA) and blood oxygenation level (fMRI). Images in both modalities are being obtained from the same subjects, under the same experimental conditions. However, recordings under both modalities are not performed simultaneously. One first aim of this project is to validate the two imaging methods under very simple and well-established experimental conditions. For example, when using visual stimulation, both methods should at least localize the same areas of the involved visual cortex. A second and more important aim of this project is to analyze the images obtained from language experiments. It is expected that both imaging methods will localize some common brain areas, but more importantly, there will be brain areas unique to each modality. If the same brain areas, unique to each modality, appear robustly and consistently over several subjects, then the existence of new functional connections are established. The importance of these results is that neither method on its own (nor fMRI, nor LORETA) would have been capable of revealing such functional connections in the brain.
Publications / Publikationen Pascual-Marqui, R.D., Michel, C.M., and Lehmann, D. (1994) Low resolution electromagnetic tomography: a new method for localizing electrical activity in the brain. International Journal of Psychophysiology, 18:49-65.

RD Pascual-Marqui, D Lehmann, T Koenig, K Kochi, MCG Merlo, D Hell, M Koukkou (1999) Low Resolution Brain Electromagnetic Tomography (LORETA) Functional Imaging in Acute, Neuroleptic-Naive, First-Episode, Productive Schizophrenics; Psychiatry Research: Neuroimaging; [accepted for publication].

Pascual-Marqui RD. Michel CM. Lehmann D. Low resolution electromagnetic tomography: a new method for localizing electrical activity in the brain. International Journal of Psychophysiology. 18(1):49-65, 1994 Oct.

Keywords / Suchbegriffe Neuroimaging, EEG, LORETA, fMRI
Project leadership and contacts /
Projektleitung und Kontakte
Kieko Kochi (Project Leader) kieko@access.uzh.ch
R. D. Pascual-Marqui, PhD (Project Leader) pascualm@key.uzh.ch
Lic.phil. Deborah Vitacco vitacco@kispi.uzh.ch
Prof. Dr. E. Martin martin@kispi.uzh.ch
Funding source(s) /
Unterstützt durch
Stiftung KEY Institute
 
Duration of Project / Projektdauer Jan 1998 to Dec 2001